BDBM595830 US11591336, Compound 253

SMILES COC(=O)n1nc(N2CCCc3ncccc23)c2ncc(nc12)N1CCC2(CO[C@@H](C)[C@H]2N)CC1

InChI Key InChIKey=DVFUKOPTCVJDPK-MGPUTAFESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 595830   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research

US Patent
LigandPNGBDBM595830(US11591336, Compound 253)
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent