BDBM595832 US11591336, Compound 13::US11629145, Compound 11
SMILES CC1(N)CCN(CC1)c1cnc2c(Sc3cccc(Cl)c3Cl)n[nH]c2n1
InChI Key InChIKey=JTHMZNHORYALTR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 595832
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair