BDBM595837 US11591336, Compound 135
SMILES C[C@@H]1Cc2ccccc2N1c1n[nH]c2nc(cnc12)N1CCC(C)(CN)CC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 595837
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair