BDBM596392 5-{3-(cyanomethyl)-3-[4- (7H-pyrrolo[2,3- d]pyrimidin-4-yl)-1H- pyrazol-1-yl]azetidin-1- yl}-N-isopropylpyrazine- 2-carboxamide::US11596632, Comp. No. 15

SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1nccc2[nH]ccc12

InChI Key InChIKey=DXOJNFQNPMHOAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596392   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM596392(5-{3-(cyanomethyl)-3-[4- (7H-pyrrolo[2,3- d]pyrimi...)
Affinity DataIC50: <10nMAssay Description:JAK1 pathway inhibitors that can be used for the treatment of cytokine-related diseases or disorders are tested for inhibitory activity of JAK target...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent