BDBM598937 3-[4-amino-5- (trifluoromethyl) pyrrolo[2,1- f][1,2,4]triazin-7- yl]-N-[(3R)-3-(4- chlorophenyl)-3- hydroxypropyl] benzamide::US11618753, Example 73

SMILES Nc1ncnn2c(cc(c12)C(F)(F)F)-c1cccc(c1)C(=O)NCC[C@@H](O)c1ccc(Cl)cc1

InChI Key InChIKey=XQXXXANFFVSVEY-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598937   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM598937(3-[4-amino-5- (trifluoromethyl) pyrrolo[2,1- f][1,...)
Affinity DataIC50:  1.40E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent