BDBM602706 2-[1-[2-(6-Azaspiro[2.5]octan-6-yl)-6-fluoro-3-methyl-4-oxo-chromen-8-yl]ethylamino]benzoic acid::US11649227, Example 328::US20230286960, Example 328

SMILES C[C@H](Nc1ccccc1C(O)=O)c1cc(F)cc2c1oc(N1CCC3(CC3)CC1)c(C)c2=O

InChI Key InChIKey=NKELAMNRVSBFNL-INIZCTEOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602706   

LigandPNGBDBM602706(2-[1-[2-(6-Azaspiro[2.5]octan-6-yl)-6-fluoro-3-met...)
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602706(2-[1-[2-(6-Azaspiro[2.5]octan-6-yl)-6-fluoro-3-met...)
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602706(2-[1-[2-(6-Azaspiro[2.5]octan-6-yl)-6-fluoro-3-met...)
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602706(2-[1-[2-(6-Azaspiro[2.5]octan-6-yl)-6-fluoro-3-met...)
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent