BDBM604057 US11660293, Example 162::US11660293, Example 164

SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1nc(C)sc1-c1ncccn1

InChI Key InChIKey=XDXYXPLVHKKDNY-OEWQXJJUSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 604057   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604057(US11660293, Example 162 | US11660293, Example 164)
Affinity DataKi:  1.17nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604057(US11660293, Example 162 | US11660293, Example 164)
Affinity DataKi:  1.48nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604057(US11660293, Example 162 | US11660293, Example 164)
Affinity DataKi:  2.09E+3nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604057(US11660293, Example 162 | US11660293, Example 164)
Affinity DataKi:  2.57E+3nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent