BDBM60536 BDBM50399283::US9102622, 13.2

SMILES FS(=O)(=O)CCCCCCCc1cccc(OCc2ccccc2)c1

InChI Key InChIKey=CEOCDYLHZFETSF-UHFFFAOYSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 60536   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of Connecticut

US Patent
LigandPNGBDBM60536(BDBM50399283 | US9102622, 13.2)
Affinity DataKi:  39nM ΔG°:  -10.5kcal/mole IC50:  165nMT: 2°CAssay Description:All compound solutions are made to a concentration of 10 mM in DMSO. To test the stability of the compounds in enzyme assay conditions, 25 nmoles of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of Connecticut

US Patent
LigandPNGBDBM60536(BDBM50399283 | US9102622, 13.2)
Affinity DataKi:  39nM ΔG°:  -10.5kcal/mole IC50:  165nMT: 2°CAssay Description:All compound solutions are made to a concentration of 10 mM in DMSO. To test the stability of the compounds in enzyme assay conditions, 25 nmoles of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of Connecticut

US Patent
LigandPNGBDBM60536(BDBM50399283 | US9102622, 13.2)
Affinity DataKi:  46nM ΔG°:  -10.4kcal/mole IC50:  193nMT: 2°CAssay Description:All compound solutions are made to a concentration of 10 mM in DMSO. To test the stability of the compounds in enzyme assay conditions, 25 nmoles of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(MOUSE)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM60536(BDBM50399283 | US9102622, 13.2)
Affinity DataKi:  99nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM60536(BDBM50399283 | US9102622, 13.2)
Affinity DataKi:  335nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM60536(BDBM50399283 | US9102622, 13.2)
Affinity DataIC50:  752nMAssay Description:Inhibition of recombinant human hexahistidine-tagged MGL expressed in Escherichia coli using AHMMCE as substrate after 15 mins by medium throughput f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed