BDBM605825 US11680056, Example 10

SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1cc(nc(n1)C(C)(C)O)C1CC1

InChI Key InChIKey=LQEBRIYADKIURD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605825   

TargetMAP kinase-activated protein kinase 2 [46-400](Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM605825(US11680056, Example 10)
Affinity DataIC50:  5.01E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-activated protein kinase 2 [46-400](Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM605825(US11680056, Example 10)
Affinity DataIC50:  1.59E+3nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent