BDBM606211 US11685719, Example 3A::US11685719, Example 3B

SMILES COCc1cc(OCc2ncc(F)cc2F)c(Cl)c(=O)n1-c1cc(ncc1C)-n1cccc(c1=O)C(C)(C)O

InChI Key InChIKey=NWGBRDDTFZTOOA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 606211   

TargetMitogen-activated protein kinase 14/1(Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM606211(US11685719, Example 3A | US11685719, Example 3B)
Affinity DataIC50:  6.31nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM606211(US11685719, Example 3A | US11685719, Example 3B)
Affinity DataIC50: >3.16E+5nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14/1(Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM606211(US11685719, Example 3A | US11685719, Example 3B)
Affinity DataIC50: >1.00E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM606211(US11685719, Example 3A | US11685719, Example 3B)
Affinity DataIC50:  5.01E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent