BDBM606217 US11685719, Example 6

SMILES CCOC(=O)C(C)(C)n1nc(ccc1=O)-c1cc(c(C)cn1)-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O

InChI Key InChIKey=ORNISAOKGBZAIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 606217   

LigandPNGBDBM606217(US11685719, Example 6)
Affinity DataIC50:  6.31E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14/1(Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM606217(US11685719, Example 6)
Affinity DataIC50:  20nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent