BDBM608214 US11691971, Example 6
SMILES O=C(Nc1cc(Nc2cccc(c2)-c2cnn(c2)C2CCOCC2)c2c(cc[nH]c2=O)n1)C1CC1
InChI Key InChIKey=IWCHEESLSSKISA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 608214
Affinity DataIC50: 5.50E+3nMAssay Description:JAK2 JH1 binding assay utilizes catalytic domain (JH1, amino acids 826-1132) of human JAK2 expressed as N-terminal FLAG-tagged, biotinylated protein ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:JAK2 JH2-V617F binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human V617F mut...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair