BDBM608345 US11691989, Compound 3::Z)-15-chloro-96-fluoro-13,25,25,61-tetramethyl- 25,26-dihydro-11H,24H,61H-10-oxa-4,8-dithia- 1(4,1)-indola-2(3,2)-pyrrolo[1,2-b]pyrazola- 6(3,5)-pyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid

SMILES Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CSCc5nn6CC(C)(C)Cc6c5-c5c(Cl)ccc2c15)nn4C)cc1cc(F)ccc31

InChI Key InChIKey=ALAUWSGVPKNNSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608345   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608345(US11691989, Compound 3 | Z)-15-chloro-96-fluoro-13...)
Affinity DataIC50:  14nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent