BDBM608359 (Z)-15-chloro-96-fluoro-61-isopropyl-13,21,25- trimethyl-11H,21H,61H-10-oxa-4,8-dithia- 1(4,1)-indola-2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 17

SMILES CC(C)n1nc2CSCc3nn(C)c(C)c3-c3c(Cl)ccc4n(CCCOc5cc(SCc1c2)cc1cc(F)ccc51)c(C(O)=O)c(C)c34

InChI Key InChIKey=FFKOSRSBPJLCJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608359   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608359((Z)-15-chloro-96-fluoro-61-isopropyl-13,21,25- tri...)
Affinity DataIC50:  15nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent