BDBM608383 (Z)-15-chloro-96-fluoro-13,21,25,61- tetramethyl-4-sulfamoyl-11H,21H,61H-10-oxa- 8-thia-4-aza-1(4,1)-indola-2(4,3),6(3,5)- dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 39

SMILES COC(=O)c1c(C)c2c3-c4c(C)n(C)nc4CN(Cc4cc(CSc5cc(OCCCn1c2ccc3Cl)c1ccc(F)cc1c5)n(C)n4)S(N)(=O)=O

InChI Key InChIKey=KTIJTAFZQYGNPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608383   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608383((Z)-15-chloro-96-fluoro-13,21,25,61- tetramethyl-4...)
Affinity DataIC50:  9nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent