BDBM608817 US11702411, Compound 1::US11702411, Example 1
SMILES N[C@@H]1CCCC11CCN(CC1)c1ncc(nc1CO)-c1ccnc(Cl)c1Cl
InChI Key InChIKey=HSLSZACYMZYPEX-OAHLLOKOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 608817
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines
US Patent
Revolution Medicines
US Patent
Affinity DataIC50: 275nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines
US Patent
Revolution Medicines
US Patent
Affinity DataIC50: 145nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair