BDBM608866 US11702411, Compound 5::[6-[(2-amino-3-chloro-4-pyridyl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-2-pyridyl]methanol.
SMILES C[C@@H]1OCC2(CCN(CC2)c2ccc(Sc3ccnc(N)c3Cl)nc2CO)[C@@H]1N
InChI Key InChIKey=GBNRSWMEOVNIIT-KPZWWZAWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608866
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines
US Patent
Revolution Medicines
US Patent
Affinity DataIC50: <50nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair