BDBM608867 US11702411, Compound 6::{3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-6-(5,6-dichloro-2H-1,3-benzodioxol-4-yl)pyrazin-2-yl}methanol.

SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(nc2CO)-c2c3OCOc3cc(Cl)c2Cl)[C@@H]1N

InChI Key InChIKey=IVSLSFSODOEMJD-JEOXALJRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608867   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM608867(US11702411, Compound 6 | {3-[(3S,4S)-4-amino-3-met...)
Affinity DataIC50:  275nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent