BDBM609045 US11702411, Compound 20
SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(nc2CO)-c2ccc3[nH]ncc3c2)[C@@H]1N
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 609045
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines
US Patent
Revolution Medicines
US Patent
Affinity DataIC50: 275nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair