BDBM609052 US11702411, Compound 27
SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc(NC4CCOCC4)c3Cl)nc2CO)[C@@H]1N
InChI Key InChIKey=FHZWVDJXBJOFRD-YCRPNKLZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 609052
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines
US Patent
Revolution Medicines
US Patent
Affinity DataIC50: <50nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair