BDBM609880 (rac)-(2s,4s)-2-(6-(4-(1-Methylcyclopropyl)phenyl)-3- azabicyclo[4.1.0]heptane-3-carbonyl)-7-oxa-5-azaspiro[3.4]octan-6-one::US11708359, Example 69
SMILES CC1(CC1)c1ccc(cc1)C12CC1CN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2
InChI Key InChIKey=SPLKUAIQKOLIFW-QGHRMTQGSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 609880
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0340nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair