BDBM613838 5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-N-(3-fluoropyridin-4-yl)furan-2-carboxamide::US11739078, Compound 103::US11739078, Compound A-25

SMILES Fc1ccc(cc1)-c1ncn(C2CCCC2)c1-c1ccc(o1)C(=O)Nc1ccncc1F

InChI Key InChIKey=ZGCQRUODVWMXSM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 613838   

TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613838(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50:  2nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613838(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50:  13.4nMAssay Description:The MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 uM, 10 mM MgAcetate and [gamma-33P-ATP] (specific activity and concentration as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613838(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50:  1.96nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent