BDBM613868 5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-N-(3-methoxypyridin-4-yl)furan-2-carboxamide::US11739078, Compound A-39

SMILES COc1cnccc1NC(=O)c1ccc(o1)-c1c(ncn1C1CCCC1)-c1ccc(F)cc1

InChI Key InChIKey=KDQBVTAHXVNGBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 613868   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613868(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50: <10nMAssay Description:The MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 uM, 10 mM MgAcetate and [gamma-33P-ATP] (specific activity and concentration as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613868(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50:  1.29nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent