BDBM613877 4-(4-(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)furan-2-carboxamido)-3-fluorophenyl)-1-methylpiperazin-1-ium::US11739078, Compound A-52

SMILES C[NH+]1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)-c2c(ncn2C2CCCC2)-c2ccc(F)cc2)c(F)c1

InChI Key InChIKey=LKJUBIURVPZKNJ-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 613877   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613877(4-(4-(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imida...)
Affinity DataIC50: <10nMAssay Description:The MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 uM, 10 mM MgAcetate and [gamma-33P-ATP] (specific activity and concentration as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613877(4-(4-(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imida...)
Affinity DataIC50:  2.80nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent