BDBM615107 US20230271945, Compound 26

SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(F)cc(F)cc12)-c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615107   

TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615107(US20230271945, Compound 26)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615107(US20230271945, Compound 26)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent