BDBM616088 US20230271964, Example 1-45

SMILES Cc1cc(cc(CO)n1)-c1c(nc(N)n2c1nn(Cc1ccn(C)n1)c2=O)-c1ccccc1

InChI Key InChIKey=LXZJDYBHHSOSIT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616088   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616088(US20230271964, Example 1-45)
Affinity DataKi:  0.501nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616088(US20230271964, Example 1-45)
Affinity DataKi:  63.1nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent