BDBM618602 US11760752, Compound NB-1-089

SMILES Cc1cc(Oc2ccc(Cn3nc(C(=O)NS(=O)(=O)c4ccc(NCc5ccco5)c(c4)[N+]([O-])=O)c4cc(Cl)ccc34)cc2)cc(C)c1Cl

InChI Key InChIKey=CYTGPWSUEKDDBJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 618602   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM618602(US11760752, Compound NB-1-089)
Affinity DataKi:  260nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM618602(US11760752, Compound NB-1-089)
Affinity DataKi:  266nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM618602(US11760752, Compound NB-1-089)
Affinity DataKi:  551nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent