BDBM618965 (3S)-3-cyano-N-[4-(3-cyanophenyl)-5-(2,6-dimethyl-4-pyridyl)thiazol-2-yl]-3-methyl-pyrrolidine-1-carboxamide::US20230293517, Example 27b

SMILES Cc1cc(cc(C)n1)-c1sc(NC(=O)N2CC[C@@](C)(C2)C#N)nc1-c1cccc(c1)C#N

InChI Key InChIKey=SMDAWUUWLRYYSQ-XMMPIXPASA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 618965   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618965((3S)-3-cyano-N-[4-(3-cyanophenyl)-5-(2,6-dimethyl-...)
Affinity DataKi:  0.140nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618965((3S)-3-cyano-N-[4-(3-cyanophenyl)-5-(2,6-dimethyl-...)
Affinity DataKi:  1nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618965((3S)-3-cyano-N-[4-(3-cyanophenyl)-5-(2,6-dimethyl-...)
Affinity DataKi:  33nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618965((3S)-3-cyano-N-[4-(3-cyanophenyl)-5-(2,6-dimethyl-...)
Affinity DataKi:  271nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent