BDBM620309 US20230295182, Example 1.41::US20230295182, Example 1.42::tert-butyl ((5r,8R)-3-(((2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3- methoxy-4-(4-(2,3,4-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H- pyran-2-yl)methyl)-1-oxa-2-azaspiro[4.5]dec-2-en-8-yl)carbamate

SMILES COC1=C(N2C[C@@H](NN2)c2ccc(F)c(F)c2F)C(O)=C(CO)O[C@@H]1CC1=NO[C@@]2(C1)CC[C@@H](CC2)NC(=O)OC(C)(C)C

InChI Key InChIKey=ILSGEWGVZPFLFO-SKAHHCHISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 620309   

TargetGalectin-3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620309(US20230295182, Example 1.41 | US20230295182, Examp...)
Affinity DataIC50:  12nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGalectin-1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620309(US20230295182, Example 1.41 | US20230295182, Examp...)
Affinity DataIC50:  850nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGalectin-1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620309(US20230295182, Example 1.41 | US20230295182, Examp...)
Affinity DataIC50:  300nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGalectin-3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620309(US20230295182, Example 1.41 | US20230295182, Examp...)
Affinity DataIC50:  132nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent