BDBM620751 (8-syn)-3-(6-chloro-2-{[1-(2- hydroxy-2-methylpropyl)- 1H-pyrazol-4-yl]amino} quinazolin-7-yl)-8-methyl- 3-azabicyclo[3.2.1]octan-8-ol::US20230303540, Example Ex-3.32
SMILES CC(C)(O)Cn1cc(Nc2ncc3cc(Cl)c(cc3n2)N2C[C@@H]3CC[C@H](C2)[C@]3(C)O)cn1
InChI Key InChIKey=FFPOYHUZXJZYGJ-MICWEPACSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 620751
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 0.393nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair