BDBM620956 (4S)-4-methyl-3-{2-[(4,5,6,7- tetrahydropyrazolo[1,5- a]pyridin-3-yl)amino]quinazolin- 7-yl}-1,3-oxazolidin-2-one::US20230303540, Example Ex-8.13

SMILES C[C@H]1COC(=O)N1c1ccc2cnc(Nc3cnn4CCCCc34)nc2c1

InChI Key InChIKey=CEOMKWUBXBTJDO-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620956   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM620956((4S)-4-methyl-3-{2-[(4,5,6,7- tetrahydropyrazolo[1...)
Affinity DataIC50:  0.625nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent