BDBM620995 (6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-yl)amino)pyridine-3-yl)(4-ethylpiperazine-1-yl)ketone::US20230303553, Example 1

SMILES CCN1CCN(CC1)C(=O)c1ccc(Nc2ncc(F)c(n2)-c2ccc3ncsc3c2)nc1

InChI Key InChIKey=SDQPABOSBRYYPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620995   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM620995((6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-y...)
Affinity DataIC50:  35nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM620995((6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-y...)
Affinity DataIC50:  144nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent