BDBM621015 (6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluoropyrimidine-2-yl)amino)pyridine-3-yl)(4-ethylpiperazine-1-yl)ketone::US20230303553, Example 42
SMILES CCN(CC)c1nc2ccc(cc2s1)-c1nc(Nc2ccc(cn2)C(=O)N2CCN(CC)CC2)ncc1F
InChI Key InChIKey=NVJVPUYRSSDOPO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 621015
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Jiangsu Tasly Diyi Pharmaceutical
US Patent
Affinity DataIC50: 14nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair