BDBM621824 (S)-N-((R or S)-(4- chlorophenyl)(4- fluoro-3-(trifluoro- methyl)phenyl)methyl)- 2-oxoimidazolidine-4- carboxamide::US20230312528, Example 17A

SMILES Fc1ccc(cc1C(F)(F)F)[C@@H](NC(=O)[C@@H]1CNC(=O)N1)c1ccc(Cl)cc1

InChI Key InChIKey=OKUOBJLNMMZBMG-GJZGRUSLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621824   

TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM621824((S)-N-((R or S)-(4- chlorophenyl)(4- fluoro-3-(tri...)
Affinity DataIC50:  0.600nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent