BDBM622407 US20230312576, Compound 48a-48b

SMILES CC1C=C(CCN1C(=O)Nc1cccc(Cl)c1)c1ncnc2[nH]cc(C)c12

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622407   

TargetLIM domain kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622407(US20230312576, Compound 48a-48b)
Affinity DataKi:  13.9nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLIM domain kinase 2(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622407(US20230312576, Compound 48a-48b)
Affinity DataKi:  14.1nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent