BDBM622485 US20230312576, Compound 198

SMILES CNC(=O)c1cc(Oc2cccc(NC(=O)N3CCC(=CC3)c3ncnc4[nH]cc(C)c34)c2)ccn1

InChI Key InChIKey=HCTRFFWHDWFRRD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622485   

TargetLIM domain kinase 2(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622485(US20230312576, Compound 198)
Affinity DataKi:  2.89nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLIM domain kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622485(US20230312576, Compound 198)
Affinity DataKi:  3.08nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent