BDBM629512 US20230339981, Example 200

SMILES FC(F)c1cnc(OC[C@@H]2CC[C@]3(COc4nc5N6C[C@H]7CC[C@H](N7)[C@H]6CCCc6nc(c(F)c(n4)c56)-c4cccc5ccc(F)c(C#C)c45)CCCN23)cn1

InChI Key InChIKey=YDRCDCZAPIHVCE-MPSSVVRESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629512   

TargetGTPase KRas [G12D](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM629512(US20230339981, Example 200)
Affinity DataIC50:  0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent