BDBM630941 (4S)-N-[((R or S)-5- chloro-6-cyclo- propylpyridin-3-yl)(3- chloro-2,4-difluoro- phenyl)methyl]-2- oxoimidazolidine-4- carboxamide::US11802122, Example 13A::US11802122, Example 13B

SMILES Fc1ccc(C(NC(=O)[C@@H]2CNC(=O)N2)c2cnc(C3CC3)c(Cl)c2)c(F)c1Cl

InChI Key InChIKey=BSGRKUFRCCPBFO-KNVGNIICSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 630941   

TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM630941((4S)-N-[((R or S)-5- chloro-6-cyclo- propylpyridin...)
Affinity DataIC50:  38nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for NaV1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM630941((4S)-N-[((R or S)-5- chloro-6-cyclo- propylpyridin...)
Affinity DataIC50:  1.10nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for NaV1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent