BDBM632697 US20230348450, Example 78

SMILES Cc1nc(COc2ncccn2)sc1-c1cccc(n1)-c1ccc(C(O)=O)c(c1)C#N

InChI Key InChIKey=AXYJCDMAMMTHEO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 632697   

TargetBisphosphoglycerate mutase(Homo sapiens)
Genzyme

US Patent
LigandPNGBDBM632697(US20230348450, Example 78)
Affinity DataIC50:  180nMAssay Description:The following materials were used in this assay: deionized water; Bisphosphoglycerate mutase (BPGM; Standard Buffer: 50 mM Tris, 0.01% Tween 20, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBisphosphoglycerate mutase(Homo sapiens)
Genzyme

US Patent
LigandPNGBDBM632697(US20230348450, Example 78)
Affinity DataEC50:  70nMAssay Description:The following materials were used in this assay: Tris buffer (50 mM Tris, 0.01% Tween 20, pH 7.4); cyclohexylammonium salt of 2,3-BPG (stock solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent