BDBM637532 (3-amino-6-((1rs,2RS,3SR)-2,3- dimethylcyclopropyl)-1H- pyrazolo[3,4-b]pyridin-1-yl)(2- methoxyphenyl)methanone::US20230382911, Example 44

SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)[C@@H]1[C@@H](C)[C@H]1C

InChI Key InChIKey=LFGHLCKZCHKOEZ-CDMJZVDBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637532   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637532((3-amino-6-((1rs,2RS,3SR)-2,3- dimethylcyclopropyl...)
Affinity DataIC50:  13nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent