BDBM63919 Anisomycin from Streptomyces griseolus::MLS001066392::SMR000471874::[(2R,3S,4S)-2-[(4-methoxyphenyl)methyl]-4-oxidanyl-pyrrolidin-3-yl] ethanoate::[(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate::acetic acid [(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]-3-pyrrolidinyl] ester::acetic acid [(2R,3S,4S)-4-hydroxy-2-p-anisyl-pyrrolidin-3-yl] ester::cid_253602::med.21724, Compound Anisomycin

SMILES COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1

InChI Key InChIKey=YKJYKKNCCRKFSL-RDBSUJKOSA-N

Data  4 IC50  4 EC50

PDB links: 10 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 63919   

TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataEC50:  243nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataIC50: >4.98E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataEC50:  190nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataIC50: >4.98E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataIC50: >4.97E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOrf1a protein(MERS-CoV)
University of Bonn

LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataEC50:  3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM63919(Anisomycin from Streptomyces griseolus | MLS001066...)
Affinity DataIC50: >4.97E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay