BDBM640380 Preparation of 3-((4-amino-7-((1r,4r)-4-hydroxycyclohexyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide ::US11840535, Example 22
SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cn([C@H]4CC[C@H](O)CC4)c4ncnc(N)c34)cc2C(F)(F)F)CC1
InChI Key InChIKey=XSOXPLMEUJTPMW-OGESRWMOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 640380
Affinity DataIC50: <5nMAssay Description:Specific Assay Method:Compound formulation: The test compounds were dissolved in DMSO to prepare a 20 mM stock solution. Before use, the compounds we...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Specific Assay Method:Compound formulation: The test compounds were dissolved in DMSO to prepare a 20 mM stock solution. Before use, the compounds we...More data for this Ligand-Target Pair