BDBM642227 (5-amino-5-(1-(2-oxo-2-(prop-2-yn-1- ylamino)ethyl)-1H-tetrazol-5- yl)pentyl)boronic acid::US11845767, Example 272

SMILES NC(CCCCB(O)O)c1nnnn1CC(=O)NCC#C

InChI Key InChIKey=KGEPAUWCNQIQHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 642227   

TargetArginase-2, mitochondrial(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642227((5-amino-5-(1-(2-oxo-2-(prop-2-yn-1- ylamino)ethyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642227((5-amino-5-(1-(2-oxo-2-(prop-2-yn-1- ylamino)ethyl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent