BDBM644517 5-(2-(4-((3- bromo-4- (trifluoro- methoxy) benzyl)amino) butoxy)ethoxy) benzo[c][2,6] naphthyridine- 8-carboxylic acid::US11866436, Example 112

SMILES OC(=O)c1ccc2c(c1)nc(OCCOCCCCNCc1ccc(OC(F)(F)F)c(Br)c1)c1ccncc21

InChI Key InChIKey=ZTXIJZHBTZODLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644517   

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644517(5-(2-(4-((3- bromo-4- (trifluoro- methoxy) benzyl)...)
Affinity DataIC50:  172nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644517(5-(2-(4-((3- bromo-4- (trifluoro- methoxy) benzyl)...)
Affinity DataIC50:  0.411nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent