BDBM64566 US9428505, Compound 10

SMILES Cc1cc(cc(C)c1CCS(=O)(=O)N1CCC2(CC1)N=C(NC2=O)c1ccc(OC(F)(F)F)cc1)N1C(=O)NC(=O)C11COC1

InChI Key InChIKey=WMHJWHBMOVKVON-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 64566   

TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rattus norvegicus (Rat))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM64566(US9428505, Compound 10)
Affinity DataEC50:  1.20E+4nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetParathyroid hormone [32-65](Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM64566(US9428505, Compound 10)
Affinity DataEC50:  2.10E+4nMpH: 7.4Assay Description:HKRK-B7 or LLC-PK1 cells were seeded into a 96-well plate at 1×105 cells/well and incubated overnight. On the following day, 50 μl of cAMP assay...More data for this Ligand-Target Pair
In DepthDetails US Patent