BDBM646014 (2S,4R)-4-hydroxy-1-((2S)-2-(2-(4-((2-(2- hydroxyphenyl)-5,6,6a,7,9,10-hexahydro-8H- pyrazino[1',2':4,5]pyrazino[2,3-c]pyridazin-8- yl)methyl)piperidin-1-yl)acetamido)-3,3- dimethylbutanoyl)-N-((S)-1-(4-(4- methylthiazol-5-yl)phenyl)ethyl)pyrrolidine- 2-carboxamide (Mixture of Diastereomers at *)::US20240018158, Example 3

SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CN1CCC(CN2CCN3C(CNc4nnc(cc34)-c3ccccc3O)C2)CC1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

InChI Key InChIKey=FORYHNQUNVCCNB-YRSQTDLFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646014   

TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM646014((2S,4R)-4-hydroxy-1-((2S)-2-(2-(4-((2-(2- hydroxyp...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (PerkinElmer ProxiPlate Plu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent