BDBM646401 US11878973, Example 85
SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)N1CCC[C@H](F)C1
InChI Key InChIKey=UNFZXULNSAVVKO-FQEVSTJZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 646401
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 70nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair