BDBM647516 US20240025893, Example b-04-42

SMILES CCCOCc1ncc(cn1)-c1ccc2nc(NC(=O)[C@@H]3C[C@@H](C3)N3CCN(C[C@@H]3C)C(=O)c3cc(C)ccn3)sc2c1

InChI Key InChIKey=FSDZCEHGNLKGKW-UMXIMWEHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647516   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Asahi Kasei Pharma

US Patent
LigandPNGBDBM647516(US20240025893, Example b-04-42)
Affinity DataIC50:  0.490nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent