BDBM647850 US20240025919, Compound 80
SMILES CCc1cccc2cc(O)cc(-c3nc4O[C@@H](C)[C@@H]5[C@@H]6CC[C@H](CN5c5nc(OC[C@@]78CCCN7CC(=C)C8)nc(c3F)c45)N6)c12
InChI Key InChIKey=OCXITLQCVGLINJ-KUXSHPFJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 647850
Affinity DataIC50: 0.0680nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Affinity DataIC50: 3.39nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1-mediated nucleotide exchange in KRAS WT. In this assay, the SOS1-promote...More data for this Ligand-Target Pair