BDBM649810 US20240043403, Example 123::US20240043403, Example 47

SMILES CNC[C@@H]1CN(CCN1C)c1c(NC(=O)c2ccn(n2)-c2ccnnc2)ccc(Oc2ccccc2F)c1C(F)(F)F

InChI Key InChIKey=OVOPLATXDOHPBM-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649810   

TargetDiacylglycerol kinase delta(Human)
Astellas Pharma

US Patent
LigandPNGBDBM649810(US20240043403, Example 123 | US20240043403, Exampl...)
Affinity DataIC50:  4nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK ξ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol kinase delta(Human)
Astellas Pharma

US Patent
LigandPNGBDBM649810(US20240043403, Example 123 | US20240043403, Exampl...)
Affinity DataIC50:  6.70nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK ξ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent